Dupuytren Contracture eMedicine Rheumatology

Description: ynonyms and related keywords: Dupuytren contracture, palmar fascia, finger contracture, palmar fasciotomy, fasciectomy, dermofasciectomy, fibroblast proliferation, myofibroblasts, collagen deposition, type III collagen, basic fibroblast growth factor, platelet-derived growth factor, transforming growth factor-beta, glycosaminoglycans, metacarpophalangeal joint, MCP joint, proximal interphalangeal joint, PIP joint, distal interphalangeal joint, DIP joint, plantar fasciitis, Peyronie disease, trisomy 8 abnormality, trisomy 8 syndrome, palmar tendinitis, reflex sympathetic dystrophy
Dupuytren contracture is a benign, slowly progressive fibroproliferative disease of the palmar fascia that has no clear etiology or pathogenesis. Plater first described this condition in 1614, but it was Dupuytren who presented a meticulous anatomical study in 1831 that established the palmar fascia as the site of origin. The site of origin distinguishes it from other causes of finger contracture. Dupuytren also devised an effective surgical approach through palmar fasciotomy.