Legg-Calve-Perthes Disease OMIM

Description: LEGG-CALVE-PERTHES DISEASE Alternative titles; symbols LCPD; LCP LEGG-PERTHES DISEASE PERTHES DISEASE Legg-Calve-Perthes disease is characterized by loss of circulation to the femoral head, resulting in avascular necrosis in a growing child. Clinical pictures of the disease vary, depending on the phase of disease progression through ischemia, revascularization, fracture and collapse, and repair and remodeling of the bone. The disease occurs more frequently in boys, and most patients tend to be shorter than their peers. Both familial and isolated cases of LCP have been reported.