Previous | Next
Paget Disease eMedicine
Paget disease is a localized disorder of bone remodeling that typically begins with excessive bone resorption followed by an increase in bone formation. This osteoclastic activity followed by compensatory bone formation (osteoblastic activity) leads to a structurally disorganized mosaic of bone (woven bone), which is weaker mechanically, larger, less compact, more vascular, and more susceptible to fracture than normal adult lamellar bone.
Author/Contact: Carbone & Barrow
Submitted by: admin
Added: Fri Mar 30 2007