Previous | Next
Pagets Disease of Bone Information Diseases Database
Paget's disease of bone
may cause or feature
Symptoms and Signs
Conductive hearing loss
Sensorineural hearing loss
Acid phosphatase levels raised (plasma or serum)
Alkaline phosphatase bone isoenzyme levels raised (plasma or serum)
Cardiac and vascular conditions
Cardiac failure, high output
may be a risk factor for osteosarcoma
Paget's disease of bone: Definition(s) via UMLS
"A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry."
Source: Medical Subject Headings, 2007_2006_08_08
"disease marked by repeated episodes of increased bone resorption followed by excessive repair, resulting in weakened, deformed bones of increased mass."
Source: CRISP Thesaurus, 2006
"Paget's Disease is a disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. (On-line Medical Dictionary)"
Source: National Cancer Institute Thesaurus, 2006_03D
Type: Reference Material
Author/Contact: Not Available
Institution: Diseases Database
Submitted by: admin
Added: Fri Mar 30 2007