Heterotopic Ossification Wheeless

Description: may present w/ signs of localized inflammation or pain, elevated skin temp, ect. - tends to occur after thr, spinal injury, head injury (11%), burns, bruises; - Events leading to HO; - mesenchymal cell (XRT prevents induced differentiation) - osteoblast - matrix (EHDP) - osteocyte - HO following THR: - HO of the elbow: - HO following spinal cord trauma: - radiographically develops in 3-5% of patients, 1-4 mo (or upto 18 mo) after injury; - it occurs below the level of the injury, usually at major joints; - incidence is 40% (1/2 of these are clinically significant); - after transection of spinal cord, ossification often takes place in soft tissues adjacent to large joints; - lower extremities are particularly suseptible & most dramatic changes are seen in Knee> Pelvis> Hip; - characteristic finding is a bilateral accretion of well defined bone which encircle the joints;