Histiocytosis X Disease Database

Description: 6 synonyms or equivalents were found. Histiocytosis X aka/or Langerhans cell histiocytosis aka/or Letterer-Siwe syndrome aka/or Schueller-Christian disease aka/or Eosinophilic granuloma aka/or Hand-Schuller-Christian disease may cause or feature Miscellaneous syndromes Bone cyst Bone lysis Hepatocellular jaundice Orbital mass Symptoms and Signs Breathlessness Exophthalmos Gum pathology Haemoptysis Hepatomegaly Lymphadenopathy Mastoiditis Oral ulceration Platyspondyly Rash Short stature Splenomegaly Suppurative otitis media Tooth loss Haematological abnormalities Leucoerythroblastic anaemia Neutropenia Red cell production reduced Thrombocytopenia Biochemical abnormalities Diabetes insipidus, non-nephrogenic Hepatocellular jaundice Histopathological abnormalities Pulmonary fibrosis X-ray abnormalities Periosteal reaction Endocrine conditions Hypopituitarism Malignant neoplastic conditions Bone metastases Respiratory conditions Pneumothorax Pulmonary fibrosis Histiocytosis X: Definition(s) via UMLS: - "The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell."