Wheeless Arthrogryposis Multiplex Congenita Amyoplasia

Description: musculoskeletal dz is characterized by congenital immobility of multiple joints.
- there may be as many as 10 to 20 specific arthrogrypotic disorders, all with similar joint manifestations;
- believed to be caused by oligohydrmnios & conditions limiting fetal movement;
- joint develops in arthrogryposis multiplex congenita, but periarticular soft tissue structures become fibrotic, leading to development of an incomplete fibrous ankylosis;