Metatropic Dysplasia

Description: A changing clinical picture characterizes this condition as the disease progresses over time. The child initially has shortened limbs and the trunk height is preserved (short-limbed dwarfism). As the condition progresses, kyphoscoliosis of the spine develops that decreases trunk height (short-trunk dwarfism). Apparent shortening of the limbs also occurs over time, due to progressive joint contractures. The word “Metatropic” is derived from the Greek word “Metatropos”, meaning changing form.